C110R (p.Cys110Arg) variant of IL2RB (P14784)
C110R (p.Cys110Arg) in IL2RB (P14784) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data.
C110R (p.Cys110Arg) variant details
- p.Cys110Arg
- ExAC rs758258445
- gnomAD rs758258445
- Missense
- Variant Prioritization Score for Impact Estimate 0.568
- REVEL 0.53
- CADD 24.50
- PolyPhen-2 0.77
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)