A24S (p.Ala24Ser) variant of IL2RB (P14784)
A24S (p.Ala24Ser) in IL2RB (P14784) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data.
A24S (p.Ala24Ser) variant details
- p.Ala24Ser
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.448
- REVEL 0.36
- CADD 2.84
- PolyPhen-2 0.24
- SIFT 0.17
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)