W131G (p.Trp131Gly) variant of IL2RA (P01589)
W131G (p.Trp131Gly) in IL2RA (P01589) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
W131G (p.Trp131Gly) variant details
- p.Trp131Gly
- ExAC rs779802160
- TOPMed rs779802160
- gnomAD rs779802160
- Missense
- Variant Prioritization Score for Impact Estimate 0.51
- REVEL 0.42
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available