V16L (p.Val16Leu) variant of IL2RA (P01589)
V16L (p.Val16Leu) in IL2RA (P01589) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
V16L (p.Val16Leu) variant details
- p.Val16Leu
- ExAC rs751620727
- TOPMed rs751620727
- gnomAD rs751620727
- Missense
- Variant Prioritization Score for Impact Estimate 0.175
- REVEL 0.12
- CADD 14.50
- PolyPhen-2 0.82
- SIFT 0.10
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available