T35I (p.Thr35Ile) variant of IL2RA (P01589)
T35I (p.Thr35Ile) in IL2RA (P01589) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
T35I (p.Thr35Ile) variant details
- p.Thr35Ile
- ExAC rs763638163
- gnomAD rs763638163
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.21
- CADD 14.60
- PolyPhen-2 0.99
- SIFT 0.08
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available