S120R (p.Ser120Arg) variant of IL2RA (P01589)
S120R (p.Ser120Arg) in IL2RA (P01589) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
S120R (p.Ser120Arg) variant details
- p.Ser120Arg
- gnomAD rs1364586699
- Missense
- Variant Prioritization Score for Impact Estimate 0.0626
- REVEL 0.04
- CADD 6.20
- PolyPhen-2 0.06
- SIFT 0.01
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available