R126K (p.Arg126Lys) variant of IL2RA (P01589)
R126K (p.Arg126Lys) in IL2RA (P01589) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
R126K (p.Arg126Lys) variant details
- p.Arg126Lys
- gnomAD rs1234367529
- Missense
- Variant Prioritization Score for Impact Estimate 0.0738
- REVEL 0.04
- CADD 7.00
- PolyPhen-2 0.02
- SIFT 0.54
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available