Q110L (p.Gln110Leu) variant of IL2RA (P01589)
Q110L (p.Gln110Leu) in IL2RA (P01589) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
Q110L (p.Gln110Leu) variant details
- p.Gln110Leu
- TOPMed rs1445854585
- gnomAD rs1445854585
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.07
- CADD 9.36
- PolyPhen-2 0.52
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available