P122A (p.Pro122Ala) variant of IL2RA (P01589)
P122A (p.Pro122Ala) in IL2RA (P01589) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
P122A (p.Pro122Ala) variant details
- p.Pro122Ala
- ExAC rs753336611
- gnomAD rs753336611
- Missense
- Variant Prioritization Score for Impact Estimate 0.0719
- REVEL 0.07
- CADD 2.37
- PolyPhen-2 0.01
- SIFT 0.28
- Most common in the East Asian population (allele frequency 7.6e-05)
- Structural context available