P112S (p.Pro112Ser) variant of IL2RA (P01589)
P112S (p.Pro112Ser) in IL2RA (P01589) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
P112S (p.Pro112Ser) variant details
- p.Pro112Ser
- TOPMed rs1328875036
- gnomAD rs1328875036
- Missense
- Variant Prioritization Score for Impact Estimate 0.113
- REVEL 0.04
- CADD 5.97
- PolyPhen-2 0.00
- SIFT 0.34
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available