L121V (p.Leu121Val) variant of IL2RA (P01589)
L121V (p.Leu121Val) in IL2RA (P01589) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
L121V (p.Leu121Val) variant details
- p.Leu121Val
- gnomAD rs1299218705
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.10
- CADD 19.40
- PolyPhen-2 0.60
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available