L11P (p.Leu11Pro) variant of IL2RA (P01589)
L11P (p.Leu11Pro) in IL2RA (P01589) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
L11P (p.Leu11Pro) variant details
- p.Leu11Pro
- ExAC rs750706858
- gnomAD rs750706858
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.16
- CADD 16.40
- PolyPhen-2 0.36
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available