L11I (p.Leu11Ile) variant of IL2RA (P01589)
L11I (p.Leu11Ile) in IL2RA (P01589) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data and structural context.
L11I (p.Leu11Ile) variant details
- p.Leu11Ile
- TOPMed rs1170621521
- gnomAD rs1170621521
- Missense
- Variant Prioritization Score for Impact Estimate 0.0419
- REVEL 0.03
- CADD 0.02
- PolyPhen-2 0.01
- SIFT 0.17
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available