I31L (p.Ile31Leu) variant of IL2RA (P01589)
I31L (p.Ile31Leu) in IL2RA (P01589) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
I31L (p.Ile31Leu) variant details
- p.Ile31Leu
- ESP rs372125213
- ExAC rs372125213
- TOPMed rs372125213
- gnomAD rs372125213
- Missense
- Variant Prioritization Score for Impact Estimate 0.0794
- REVEL 0.09
- CADD 0.67
- PolyPhen-2 0.02
- SIFT 0.48
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available