H73Y (p.His73Tyr) variant of IL2RA (P01589)
H73Y (p.His73Tyr) in IL2RA (P01589) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
H73Y (p.His73Tyr) variant details
- p.His73Tyr
- gnomAD rs1375177673
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.20
- CADD 15.00
- PolyPhen-2 0.29
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 0.00022)
- Structural context available