F13L (p.Phe13Leu) variant of IL2RA (P01589)
F13L (p.Phe13Leu) in IL2RA (P01589) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
F13L (p.Phe13Leu) variant details
- p.Phe13Leu
- NCI-TCGA TCGA novel
- Ensembl rs2132911849
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.154
- REVEL 0.08
- CADD 8.04
- PolyPhen-2 0.01
- SIFT 0.31
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available