Y15C (p.Tyr15Cys) variant of IL23R (Interleukin-23 receptor)
Y15C (p.Tyr15Cys) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
Y15C (p.Tyr15Cys) variant details
- p.Tyr15Cys
- ExAC rs774581386
- gnomAD rs774581386
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.25
- CADD 15.30
- PolyPhen-2 0.01
- SIFT 0.17
- Most common in the South Asian population (allele frequency 0.00026)
- Structural context available