W35R (p.Trp35Arg) variant of IL23R (Interleukin-23 receptor)
W35R (p.Trp35Arg) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
W35R (p.Trp35Arg) variant details
- p.Trp35Arg
- gnomAD 1-67169374-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.461
- REVEL 0.48
- CADD 22.00
- PolyPhen-2 0.10
- SIFT 0.16
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available
- Literature evidence available