W35G (p.Trp35Gly) variant of IL23R (Interleukin-23 receptor)
W35G (p.Trp35Gly) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
W35G (p.Trp35Gly) variant details
- p.Trp35Gly
- gnomAD 1-67169374-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.62
- REVEL 0.72
- CADD 25.70
- PolyPhen-2 0.80
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available
- Literature evidence available