V4D (p.Val4Asp) variant of IL23R (Interleukin-23 receptor)
V4D (p.Val4Asp) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
V4D (p.Val4Asp) variant details
- p.Val4Asp
- gnomAD 1-67168131-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.512
- REVEL 0.51
- CADD 21.70
- PolyPhen-2 0.78
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available