V36A (p.Val36Ala) variant of IL23R (Interleukin-23 receptor)
V36A (p.Val36Ala) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
V36A (p.Val36Ala) variant details
- p.Val36Ala
- gnomAD 1-67169378-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.594
- REVEL 0.64
- CADD 25.30
- PolyPhen-2 0.75
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available