S49Y (p.Ser49Tyr) variant of IL23R (Interleukin-23 receptor)
S49Y (p.Ser49Tyr) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
S49Y (p.Ser49Tyr) variant details
- p.Ser49Tyr
- gnomAD rs1356970161
- Missense
- Variant Prioritization Score for Impact Estimate 0.729
- REVEL 0.71
- CADD 24.80
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available