R74K (p.Arg74Lys) variant of IL23R (Interleukin-23 receptor)
R74K (p.Arg74Lys) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
R74K (p.Arg74Lys) variant details
- p.Arg74Lys
- gnomAD rs1281925695
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.19
- CADD 1.94
- PolyPhen-2 0.26
- SIFT 0.46
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available