P61L (p.Pro61Leu) variant of IL23R (Interleukin-23 receptor)
P61L (p.Pro61Leu) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
P61L (p.Pro61Leu) variant details
- p.Pro61Leu
- gnomAD rs1466428054
- Missense
- Variant Prioritization Score for Impact Estimate 0.669
- REVEL 0.60
- CADD 23.60
- PolyPhen-2 0.86
- SIFT 0.05
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available