L64V (p.Leu64Val) variant of IL23R (Interleukin-23 receptor)
L64V (p.Leu64Val) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
L64V (p.Leu64Val) variant details
- p.Leu64Val
- ExAC rs747027115
- gnomAD rs747027115
- Missense
- Variant Prioritization Score for Impact Estimate 0.125
- REVEL 0.18
- CADD 0.17
- PolyPhen-2 0.10
- SIFT 0.05
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available