L64P (p.Leu64Pro) variant of IL23R (Interleukin-23 receptor)
L64P (p.Leu64Pro) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
L64P (p.Leu64Pro) variant details
- p.Leu64Pro
- ExAC rs771174962
- gnomAD rs771174962
- Missense
- Variant Prioritization Score for Impact Estimate 0.636
- REVEL 0.64
- CADD 24.40
- PolyPhen-2 0.85
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available