L17P (p.Leu17Pro) variant of IL23R (Interleukin-23 receptor)
L17P (p.Leu17Pro) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
L17P (p.Leu17Pro) variant details
- p.Leu17Pro
- TOPMed rs1241516896
- Missense
- Variant Prioritization Score for Impact Estimate 0.625
- REVEL 0.70
- CADD 24.20
- PolyPhen-2 0.88
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available