K57E (p.Lys57Glu) variant of IL23R (Interleukin-23 receptor)
K57E (p.Lys57Glu) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
K57E (p.Lys57Glu) variant details
- p.Lys57Glu
- ExAC rs779308889
- gnomAD rs779308889
- Missense
- Variant Prioritization Score for Impact Estimate 0.493
- REVEL 0.50
- CADD 25.30
- PolyPhen-2 0.89
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available