I77T (p.Ile77Thr) variant of IL23R (Interleukin-23 receptor)
I77T (p.Ile77Thr) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
I77T (p.Ile77Thr) variant details
- p.Ile77Thr
- gnomAD rs1202465423
- Missense
- Variant Prioritization Score for Impact Estimate 0.23
- REVEL 0.27
- CADD 8.50
- PolyPhen-2 0.01
- SIFT 0.17
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available