I77F (p.Ile77Phe) variant of IL23R (Interleukin-23 receptor)
I77F (p.Ile77Phe) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
I77F (p.Ile77Phe) variant details
- p.Ile77Phe
- gnomAD 1-67169500-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.343
- REVEL 0.32
- CADD 9.64
- PolyPhen-2 0.16
- SIFT 0.02
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available
- Literature evidence available