I34M (p.Ile34Met) variant of IL23R (Interleukin-23 receptor)
I34M (p.Ile34Met) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
I34M (p.Ile34Met) variant details
- p.Ile34Met
- gnomAD 1-67169373-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.374
- REVEL 0.16
- CADD 9.82
- PolyPhen-2 0.02
- SIFT 0.22
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available