I28K (p.Ile28Lys) variant of IL23R (Interleukin-23 receptor)
I28K (p.Ile28Lys) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
I28K (p.Ile28Lys) variant details
- p.Ile28Lys
- gnomAD rs1162714374
- Missense
- Variant Prioritization Score for Impact Estimate 0.669
- REVEL 0.69
- CADD 25.20
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available