I12T (p.Ile12Thr) variant of IL23R (Interleukin-23 receptor)
I12T (p.Ile12Thr) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
I12T (p.Ile12Thr) variant details
- p.Ile12Thr
- Ensembl rs1646896298
- Missense
- Variant Prioritization Score for Impact Estimate 0.397
- REVEL 0.49
- CADD 16.70
- PolyPhen-2 0.37
- SIFT 0.03
- Most common in the South Asian population (allele frequency 5.8e-05)
- Structural context available