H22Y (p.His22Tyr) variant of IL23R (Interleukin-23 receptor)
H22Y (p.His22Tyr) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
H22Y (p.His22Tyr) variant details
- p.His22Tyr
- gnomAD rs1474792230
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.30
- CADD 16.30
- PolyPhen-2 0.13
- SIFT 0.30
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available