H22Q (p.His22Gln) variant of IL23R (Interleukin-23 receptor)
H22Q (p.His22Gln) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
H22Q (p.His22Gln) variant details
- p.His22Gln
- gnomAD 1-67168186-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.363
- REVEL 0.44
- CADD 22.10
- PolyPhen-2 0.93
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available