G70V (p.Gly70Val) variant of IL23R (Interleukin-23 receptor)
G70V (p.Gly70Val) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
G70V (p.Gly70Val) variant details
- p.Gly70Val
- ExAC rs759723554
- gnomAD rs759723554
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.38
- CADD 17.40
- PolyPhen-2 0.57
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available