G23R (p.Gly23Arg) variant of IL23R (Interleukin-23 receptor)
G23R (p.Gly23Arg) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
G23R (p.Gly23Arg) variant details
- p.Gly23Arg
- ExAC rs752478137
- TOPMed rs752478137
- gnomAD rs752478137
- Missense
- Variant Prioritization Score for Impact Estimate 0.696
- REVEL 0.65
- CADD 23.40
- PolyPhen-2 0.98
- SIFT 0.19
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available