F75L (p.Phe75Leu) variant of IL23R (Interleukin-23 receptor)
F75L (p.Phe75Leu) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
F75L (p.Phe75Leu) variant details
- p.Phe75Leu
- gnomAD 1-67169494-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.14
- CADD 6.46
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available