F18L (p.Phe18Leu) variant of IL23R (Interleukin-23 receptor)
F18L (p.Phe18Leu) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
F18L (p.Phe18Leu) variant details
- p.Phe18Leu
- TOPMed rs1353572541
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- REVEL 0.27
- CADD 17.90
- PolyPhen-2 0.14
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available