C30Y (p.Cys30Tyr) variant of IL23R (Interleukin-23 receptor)
C30Y (p.Cys30Tyr) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data, published literature, and structural context.
C30Y (p.Cys30Tyr) variant details
- p.Cys30Tyr
- gnomAD 1-67169360-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.799
- REVEL 0.81
- CADD 26.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available