C21Y (p.Cys21Tyr) variant of IL23R (Interleukin-23 receptor)
C21Y (p.Cys21Tyr) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, published literature, and structural context.
C21Y (p.Cys21Tyr) variant details
- p.Cys21Tyr
- gnomAD 1-67168182-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.686
- REVEL 0.63
- CADD 23.90
- PolyPhen-2 0.66
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available