A39T (p.Ala39Thr) variant of IL23R (Interleukin-23 receptor)
A39T (p.Ala39Thr) in IL23R (Interleukin-23 receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
A39T (p.Ala39Thr) variant details
- p.Ala39Thr
- TOPMed rs1570774918
- gnomAD rs1570774918
- Missense
- Variant Prioritization Score for Impact Estimate 0.433
- REVEL 0.43
- CADD 23.90
- PolyPhen-2 0.89
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available