L8W (p.Leu8Trp) variant of IL1RAPL1 (Q9NZN1)
L8W (p.Leu8Trp) in IL1RAPL1 (Q9NZN1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
L8W (p.Leu8Trp) variant details
- p.Leu8Trp
- ExAC rs750663388
- gnomAD rs750663388
- Missense
- Variant Prioritization Score for Impact Estimate 0.365
- REVEL 0.22
- CADD 25.00
- PolyPhen-2 0.61
- SIFT 0.01
- Population evidence available
- Structural context available