I36V (p.Ile36Val) variant of IL1RAPL1 (Q9NZN1)
I36V (p.Ile36Val) in IL1RAPL1 (Q9NZN1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
I36V (p.Ile36Val) variant details
- p.Ile36Val
- rs369272343
- ExAC rs369272343
- TOPMed rs369272343
- gnomAD rs369272343
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.09
- CADD 10.60
- PolyPhen-2 0.00
- SIFT 1.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available