D112G (p.Asp112Gly) variant of IL1RAPL1 (Q9NZN1)
D112G (p.Asp112Gly) in IL1RAPL1 (Q9NZN1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data and structural context.
D112G (p.Asp112Gly) variant details
- p.Asp112Gly
- rs759718387
- NCI-TCGA Cosmic COSV1001
- ExAC rs759718387
- gnomAD rs759718387
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.826
- AlphaMissense 1.00
- MetaLR 0.79
- MetaSVM 0.76
- PolyPhen-2 1.00
- SIFT 0.00
- MutPred 0.77
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available