A13S (p.Ala13Ser) variant of IL1RAPL1 (Q9NZN1)
A13S (p.Ala13Ser) in IL1RAPL1 (Q9NZN1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes structural context.
A13S (p.Ala13Ser) variant details
- p.Ala13Ser
- rs1240596680
- NCI-TCGA Cosmic COSV1001
- TOPMed rs1240596680
- gnomAD rs1240596680
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- AlphaMissense 0.09
- MetaLR 0.01
- MetaSVM -0.96
- PolyPhen-2 0.02
- SIFT 0.20
- MutPred 0.59
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available