W82L (p.Trp82Leu) variant of IL1R1 (Interleukin-1 receptor type 1)
W82L (p.Trp82Leu) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
W82L (p.Trp82Leu) variant details
- p.Trp82Leu
- ExAC rs748718957
- TOPMed rs748718957
- gnomAD rs748718957
- Missense
- Variant Prioritization Score for Impact Estimate 0.655
- REVEL 0.56
- CADD 26.90
- PolyPhen-2 0.83
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available