W57C (p.Trp57Cys) variant of IL1R1 (Interleukin-1 receptor type 1)
W57C (p.Trp57Cys) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data and structural context.
W57C (p.Trp57Cys) variant details
- p.Trp57Cys
- Ensembl rs1345298159
- Missense
- Variant Prioritization Score for Impact Estimate 0.828
- REVEL 0.86
- CADD 26.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available