V84L (p.Val84Leu) variant of IL1R1 (Interleukin-1 receptor type 1)
V84L (p.Val84Leu) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
V84L (p.Val84Leu) variant details
- p.Val84Leu
- gnomAD 2-102164962-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.281
- REVEL 0.13
- CADD 17.80
- PolyPhen-2 0.02
- SIFT 0.47
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available