V84I (p.Val84Ile) variant of IL1R1 (Interleukin-1 receptor type 1)
V84I (p.Val84Ile) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
V84I (p.Val84Ile) variant details
- p.Val84Ile
- gnomAD 2-102164962-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.03
- CADD 17.70
- PolyPhen-2 0.10
- SIFT 0.43
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available